Advancing prostate brachytherapy through international collaboration

ENCOMPASS is a global consortium focused on improving the quality, consistency, and outcomes of prostate brachytherapy.

The ENCOMPASS Registry forms the foundation of this initiative, enabling large-scale evaluation of clinical practice, imaging, dosimetry, toxicity, and oncologic outcomes across institutions.

Our Vision

ENCOMPASS aims to transform prostate brachytherapy by enabling global collaboration, standardising practice, and linking treatment delivery to meaningful patient outcomes.

Through coordinated data collection, methodological development, and translational research, ENCOMPASS seeks to define best practice, reduce variation, and improve the quality and consistency of care worldwide.

About ENCOMPASS

ENCOMPASS is an international prostate brachytherapy consortium bringing together clinicians, medical physicists, researchers, and institutions with a shared commitment to improving treatment quality and outcomes.

The initiative combines registry-based data infrastructure with research programs in imaging, dosimetry, treatment verification, dose accumulation, and outcome modelling.

What ENCOMPASS Does

Global Collaboration

Builds an international network of centres contributing expertise, shared priorities, and research capacity in prostate brachytherapy.

Data and Infrastructure

Establishes scalable registry infrastructure for harmonised clinical, imaging, dosimetric, toxicity, and outcome data.

Innovation and Translation

Supports development and validation of new methods in image guidance, dose accumulation, treatment verification, and quality improvement.

The ENCOMPASS Registry

The ENCOMPASS Registry is the central data platform underpinning the consortium. It captures detailed clinical, imaging, treatment, toxicity, and outcome data across centres delivering prostate brachytherapy.

By linking technical treatment delivery with patient outcomes, the registry supports benchmarking, quality improvement, collaborative research, and evidence generation for future standards of care.

What does the Registry collect?

The ENCOMPASS Registry captures the technical and clinical detail needed to understand how prostate brachytherapy is delivered and how variation in practice affects outcomes.

  • Clinical and demographic data
  • Treatment details, including HDR, LDR, monotherapy, boost, and salvage approaches
  • DICOM imaging and treatment-related dosimetry
  • Toxicity and patient-reported outcome measures
  • Biochemical control and long-term oncologic outcomes

ENCOMPASS Members

ENCOMPASS members are clinicians, medical physicists, researchers, and institutions contributing to the broader scientific direction, collaborative planning, and development of the consortium.

ENCOMPASS membership is distinct from formal registry participation. Registry participation may require local governance approval, data-sharing agreements, site initiation, and contribution of standardised data.

Registry Participation

Centres interested in formal registry participation can contribute standardised clinical, imaging, dosimetric, toxicity, and outcome data through a structured governance and site-initiation pathway.

Participation in the registry provides a pathway to data-driven benchmarking, collaborative analyses, quality improvement initiatives, and future ENCOMPASS sub-studies.

Governance and Data Security

ENCOMPASS data are managed under strict governance frameworks. Data are de-identified prior to transfer and stored securely within approved institutional infrastructure. Formal registry participation is subject to local approvals, institutional governance, and data-sharing agreements.

Leadership

Consortium Chairs

ENCOMPASS is co-led by

Joel Poder
Radiation Oncology Medical Physics Specialist
St George Hospital Cancer Care Centre, Australia

Pierre Blanchard
Radiation Oncologist
Gustave Roussy, Paris, France

Mario Terlizzi
Radiation Oncologist
Gustave Roussy, Paris, France

Coordination

International prostate brachytherapy collaboration

ENCOMPASS brings together clinical, physics, imaging, and outcomes research expertise to support coordinated international studies in prostate brachytherapy.

The initiative is coordinated through St George Hospital Cancer Care Centre, with international leadership from Gustave Roussy and a growing network of participating centres and members.

Join ENCOMPASS

ENCOMPASS is actively expanding its international membership and welcomes centres interested in prostate brachytherapy research, quality improvement, registry participation, and collaborative innovation.

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